| Date | Location | Result | |
| 03/05/19 | Charleston, S.C. (Buc Dome) | Charleston So. 71, USC Upstate 52 | Box score |
| 03/02/19 | Spartanburg, S.C. (G.B. Hodge Center) | Hampton Univ. 92, USC Upstate 71 | Box score |
| 02/27/19 | Spartanburg, S.C. (G.B. Hodge Center) | Campbell 85, USC Upstate 73 | Box score |
| 02/21/19 | Charleston, S.C. (Buccaneer Field House) | Charleston So. 92, USC Upstate 60 | Box score |
| 02/16/19 | Farmville, Va. (Willett Hall) | Longwood 83, USC Upstate 79 (OT) | Box score |
| 02/13/19 | Spartanburg, S.C. (G.B. Hodge Center) | UNC Asheville 57, USC Upstate 53 | Box score |
| 02/09/19 | Buies Creek, N.C. (Gore Arena) | Campbell 82, USC Upstate 66 | Box score |
| 02/02/19 | Spartanburg, S.C. (G.B. Hodge Center) | Charleston So. 90, USC Upstate 71 | Box score |
| 01/30/19 | Asheville, N.C. (Kimmel Arena) | UNC Asheville 71, USC Upstate 62 | Box score |
| 01/26/19 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 80, Longwood 63 | Box score |
| 01/24/19 | Hampton, Va. (HU Convocation Center) | Hampton Univ. 88, USC Upstate 70 | Box score |
| 01/21/19 | Spartanburg, S.C. (G.B. Hodge Center) | Presbyterian 68, USC Upstate 59 | Box score |
| 01/19/19 | Spartanburg, S.C. (G.B. Hodge Center) | WINTHROP 82, USC Upstate 72 | Box score |
| 01/16/19 | High Point, N.C. (Millis Center) | High Point 71, USC Upstate 54 | Box score |
| 01/12/19 | Boiling Springs, N.C. (Porter Arena) | Gardner-Webb 64, USC Upstate 59 | Box score |
| 01/10/19 | Spartanburg, S.C. (G.B. Hodge Center) | Radford 79, USC Upstate 72 | Box score |
| 01/05/19 | Clinton, S.C. (Templeton Center) | Presbyterian 64, USC Upstate 61 | Box score |
| 01/02/19 | Atlanta, Ga. (McCamish Pavilion) | Georgia Tech 79, USC Upstate 63 | Box score |
| 12/29/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 89, COKER 69 | Box score |
| 12/22/18 | Raleigh, N.C. (PNC Arena) | NC State 98, USC Upstate 71 | Box score |
| 12/19/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 85, Truett-McConnell 54 | Box score |
| 12/15/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 88, South Carolina St. 84 | Box score |
| 12/08/18 | Spartanburg, S.C. (G.B. Hodge Center) | Furman 74, USC Upstate 60 | Box score |
| 12/05/18 | Richmond, Ky. (Paul S. McBrayer Arena) | Eastern Kentucky 79, USC Upstate 77 | Box score |
| 12/01/18 | Kalamazoo, Mich. (University Arena) | USC Upstate 71, Western Michigan 66 | Box score |
| 11/28/18 | Spartanburg, S.C. (G.B. Hodge Center) | Gardner-Webb 74, USC Upstate 61 | Box score |
| 11/24/18 | Portland, Ore. (Chiles Center) | Cal Poly 75, USC Upstate 74 (OT) | Box score |
| 11/23/18 | Portland, Ore. (Chiles Center) | Texas St. 82, USC Upstate 50 | Box score |
| 11/21/18 | Portland, Ore. (Chiles Center) | Portland 73, USC Upstate 56 | Box score |
| 11/14/18 | Lexington, Va. (Cameron Hall) | VMI 78, USC Upstate 72 | Box score |
| 11/10/18 | Spartanburg, S.C. (G.B. Hodge Center) | USC Upstate 86, Brevard 43 | Box score |
| 11/06/18 | Columbia, S.C. (Colonial Life Arena) | South Carolina 65, USC Upstate 52 | Box score |