| Date | Location | Result | |
| 03/01/16 | Jacksonville, Fla. (UNF Arena) | North Florida 92, USC Upstate 69 | Box score |
| 02/25/16 | Spartanburg, S.C. (Hodge Center) | USC Upstate 72, NJIT 71 | Box score |
| 02/20/16 | Jacksonville, Fla. | UNF Arena | North Florida 81, USC Upstate 78 | Box score |
| 02/18/16 | Jacksonville, Fl. (Historic Swisher Gym) | Jacksonville 81, USC Upstate 76 | Box score |
| 02/13/16 | Spartanburg, S.C. (Hodge Center) | USC Upstate 85, Stetson 83 | Box score |
| 02/11/16 | Spartanburg, S.C. (Hodge Center) | FGCU 71, USC Upstate 64 | Box score |
| 02/06/16 | Spartanburg, S.C. (Hodge Center) | Lipscomb 78, USC Upstate 65 | Box score |
| 02/01/16 | Convocation Center (Kennesaw, Ga.) | Kennesaw State 75, USC Upstate 62 | Box score |
| 01/30/16 | Nashville, Tenn. (Allen Arena) | USC Upstate 92, Lipscomb 91 (OT) | Box score |
| 01/27/16 | Spartanburg, S.C. (Hodge Center) | Kennesaw State 78, USC Upstate 75 | Box score |
| 01/23/16 | Spartanburg, S.C. (Hodge Center) | Jacksonville 77, USC Upstate 68 | Box score |
| 01/21/16 | Spartanburg, S.C. (Hodge Center) | North Florida 78, USC Upstate 62 | Box score |
| 01/16/16 | Fort Myers, FL (Alico Arena) | FGCU 85, USC Upstate 56 | Box score |
| 01/14/16 | DeLand, Fla. (Edmunds Center) | Stetson 89, USC Upstate 86 (OT) | Box score |
| 01/09/16 | Newark, NJ - Fleisher Athletic Center | USC Upstate 80, NJIT 78 | Box score |
| 01/05/16 | Spartanburg, S.C. (Hodge Center) | USC Upstate 78, North Carolina A&T 68 | Box score |
| 01/02/16 | Spartanburg, S.C. (Hodge Center) | USC Upstate 70, UMKC 68 | Box score |
| 12/30/15 | Spartanburg, S.C. (Hodge Center) | USC Upstate 88, Lees-McRae 60 | Box score |
| 12/21/15 | Fort Collins, Colo. (Moby Arena) | Colorado State 89, USC Upstate 61 | Box score |
| 12/16/15 | Birmingham, Ala. (Bartow Arena) | UAB 96, USC Upstate 54 | Box score |
| 12/14/15 | Annapolis, Md. (Alumni Hall) | USC Upstate 66, Navy 57 | Box score |
| 12/11/15 | Spartanburg, S.C. (Hodge Center) | USC Upstate 70, North Greenville 58 | Box score |
| 12/04/15 | Greenville, N.C. (Minges Coliseum) | East Carolina 82, USC Upstate 71 | Box score |
| 12/02/15 | Greenville, S.C. (Bon Secours Arena) | Clemson 76, USC Upstate 56 | Box score |
| 11/30/15 | Spartanburg, S.C. (Hodge Center) | USC Upstate 101, Toccoa Falls 54 | Box score |
| 11/28/15 | Spartanburg, S.C. (Hodge Center) | The Citadel 88, USC Upstate 81 | Box score |
| 11/27/15 | Spartanburg, S.C. (Hodge Center) | Georgia Southern 84, USC Upstate 80 | Box score |
| 11/24/15 | Spartanburg, S.C. (Hodge Center) | Winthrop 79, USC Upstate 78 | Box score |
| 11/21/15 | Spartanburg, S.C. (Hodge Center) | Bob Jones 83, USC Upstate 79 | Box score |
| 11/19/15 | Spartanburg, S.C. (Hodge Center) | Navy 67, USC Upstate 55 | Box score |
| 11/16/15 | Clinton, S.C. (Templeton Center) | Presbyterian 74, USC Upstate 73 | Box score |
| 11/13/15 | Reed Arena (College Station, TX) | Texas A&M 104, USC Upstate 64 | Box score |